Can troponin be elevated without MI?
Can troponin be elevated without MI?
The elevated troponins in the absence of myocardial ischemia are rare; however, it can be seen in conditions such as myocarditis, pulmonary embolism, acute heart failure, sepsis and septic shock, hypovolemia, renal failure, atrial fibrillation and cardiac contusion [2, 3].
What other non ACS conditions can elevate troponin?
CARDIAC TROPONIN RELEASE UNRELATED TO ACS
- Sepsis/septic shock and systemic inflammatory response syndrome.
- Pulmonary embolism.
- Acute and chronic heart failure.
- Strenuous exercise.
- Acute pericarditis/myocarditis.
- Cardiotoxic chemotherapy.
- High frequency ablation/external current cardioversion/defibrillator shocks.
What does elevated troponin I indicate?
Very high levels of troponin are a sign that a heart attack has occurred. Most patients who have had a heart attack have increased troponin levels within 6 hours. After 12 hours, almost everyone who has had a heart attack will have raised levels. Troponin levels may remain high for 1 to 2 weeks after a heart attack.
What is Non mi troponin elevation?
Non-MI troponin elevation (nonischemic myocardial injury) The number of conditions known to cause myocardial injury through mechanisms other than myocardial ischemia (see Figure 2) is growing, especially in the current era of high-sensitivity troponin assays.
How accurate is troponin test?
The assay has high precision at low concentrations and can detect cTnI in 96.8% of healthy individuals.
What is the treatment for high troponin levels?
If troponin levels are high (elevated above normal) and the EKG indicates an acute heart attack, you may have cardiac intervention such as a catheterization with angioplasty and possibly stents, or an evaluation for coronary artery bypass graft (CABG) surgery may be required.
What is a good troponin level?
For example, the normal range for troponin I is between 0 and 0.04 ng/mL but for high-sensitivity cardiac troponin (hs-cTn) normal values are below 14ng/L. Other types of heart injury may cause a rise in troponin levels.
Which troponin is more accurate?
Cardiac troponin I appears to be a more specific marker of risk of composite cardiovascular disease and coronary heart disease, whereas cardiac troponin T is more strongly associated with risk of non–cardiovascular disease death.