What is benign Nephrosclerosis?

Benign nephrosclerosis refers to renal damage resulting from essential hypertension, usually defined as a diastolic blood pressure in excess of 90 mm Hg. Its pathogenesis is multifactorial. Genetic factors appear to be important, although no specific genetic marker has been identified.

Is benign Nephrosclerosis reversible?

Conclusions: Reversible renal insufficiency in hypertensive nephrosclerosis associated with ACE inhibitor therapy correlates with relative hypotension, is not dependent on renal artery stenosis, and can usually be managed by dose reduction.

What causes nephrosclerosis?

Hypertensive arteriolar nephrosclerosis is progressive kidney damage caused by long-standing, poorly controlled high blood pressure (hypertension). The person may develop symptoms of chronic kidney disease such as loss of appetite, nausea, vomiting, itching, and confusion.

Which disorders can lead to nephrosclerosis?

Hypertension and Aging Both Lead to Nephrosclerosis and FSGS But Kidney Histology Reveals That They Are Not the Same Entity.

What is benign hypertension?

Q: What is benign essential hypertension? A: When essential hypertension remains in its early stages for a prolonged period of time and without a specific known cause, it is known as benign essential hypertension. In this state, the condition will generally be symptomless and develop very slowly.

Is benign essential hypertension?

Term “benign hypertension” is usually slight to moderate severity and of long duration; it does not imply etiology, although most often it is considered “essential” hypertension. Benign nephrosclerosis is the term applied to the renal changes seen with long-standing benign hypertension. Usually asymptomatic.

What is benign hypertensive heart disease?

Hypertensive heart disease refers to heart conditions caused by high blood pressure. The heart working under increased pressure causes some different heart disorders. Hypertensive heart disease includes heart failure, thickening of the heart muscle, coronary artery disease, and other conditions.

Which is the best description of benign nephrosclerosis?

Benign nephrosclerosis is a gradual and prolonged deterioration of the renal arteries. First the inner layer of the walls of smaller vessels thickens, and gradually this thickening spreads to the whole wall, sometimes closing the central channel of the vessel.

How does Malignant nephrosclerosis lead to renal failure?

In malignant or accelerated hypertension, intimal changes in the renal arterial vessels lead to ischemia, increased production of renin, and exacerbation of hypertension, potentially resulting in acute renal failure that, if not treated successfully, will result in end-stage renal disease.

What is the PAS stain for benign nephrosclerosis?

In an infarcted glomerulus, the PAS stain shows a condensed, collapsed glomerular tuft without the collagenous tissue in Bowman’s space that is observed in benign nephrosclerosis (Fig. 5-29 ).

Where does nephrosclerosis occur in the human body?

See Article History. Nephrosclerosis, hardening of the walls of the small arteries and arterioles (small arteries that convey blood from arteries to the even smaller capillaries) of the kidney.