Can you have a transfusion reaction to platelets?

Allergic and anaphylactic reactions occur after platelet transfusions with similar frequency as FNHTRs. The risk of allergic reactions is between 0.09 and 21% in patients who receive platelet transfusions [16]. Allergic reactions are highly variable in severity.

What is a febrile transfusion reaction?

Nonhemolytic febrile transfusion reactions are usually caused by cytokines from leukocytes in transfused red cell or platelet components, causing fever, chills, or rigors. In the transfusion setting, a fever is defined as a temperature elevation of 1º C or 2º F.

Is it normal to have a fever after a blood transfusion?

Developing a fever after a transfusion is not serious. A fever is your body’s response to the white blood cells in the transfused blood. However, it can be a sign of a serious reaction if the patient is also experiencing nausea or chest pain.

How is a febrile transfusion reaction treated?

In febrile, nonhemolytic reactions, fever usually resolves in 15-30 minutes without specific treatment. If fever causes discomfort, oral acetaminophen (325-500 mg) may be administered. Avoid aspirin because of its prolonged adverse effect on platelet function.

What are the signs of a transfusion reaction?

The most common signs and symptoms include fever, chills, urticaria (hives), and itching. Some symptoms resolve with little or no treatment. However, respiratory distress, high fever, hypotension (low blood pressure), and red urine (hemoglobinuria) can indicate a more serious reaction.

How do you prevent a febrile Nonhemolytic transfusion reaction?

The best way to prevent severe febrile reactions is to use prestorage leukocyte reduced red blood cells and apheresis platelets. If a patient continues to have febrile reactions to leukocyte reduced single donor platelets, it may be helpful to remove plasma from the platelet unit immediately prior to transfusion.

Can my body reject blood transfusion?

Blood transfusions may be rejected by the recipient, resulting in a transfusion reaction, but such cases are relatively rare. In order to comprehend how this can happen, it is necessary to understand some basic immunology.

How long after a blood transfusion can a reaction occur?

This reaction usually occurs within six hours of receiving blood. In rare instances, bacteria may be present in the donated blood. Giving this contaminated blood to a recipient can lead to infection, shock, and death. A transfusion reaction can also occur if a person receives too much blood.

Who is at risk for febrile transfusion reaction?

Patients, who are febrile at the onset of transfusion or have been febrile in the preceding 24 hours, are more prone to febrile reactions. It is important to recognize and report febrile reactions because they may be the first indication of a septic or hemolytic transfusion reaction.

Can you have a delayed reaction to a blood transfusion?

Delayed Hemolytic Reactions Delayed hemolytic transfusion reactions can be seen several days to months after the transfusion. A decrease in hemoglobin level helps the clinician to make the diagnosis. The patient may report vague symptoms such as chills, myalgia, and low back pain.