What did Christiane Nusslein-Volhard discover?

What did Christiane Nüsslein-Volhard discover?

In 1988, Nüsslein-Volhard identified the first described morphogen, a protein coded by the gene bicoid in flies. In 1995, along with Eric F. Wieschaus and Edward B. Lewis, she received the Nobel Prize in Physiology or Medicine for the discovery of genes that establish the body plan and segmentation in Drosophila.

What is Christiane Nüsslein-Volhard famous for?

Christiane Nüsslein-Volhard, (born October 20, 1942, Magdeburg, Germany), German developmental geneticist who was jointly awarded the 1995 Nobel Prize for Physiology or Medicine with geneticists Eric F. Wieschaus and Edward B. Lewis for their research concerning the mechanisms of early embryonic development.

What did Lewis Volhard and wieschaus discover?

Using Drosophila Nüsslein-Volhard and Wieschaus were able to identify and classify a small number of genes that are of key importance in determining the body plan and the formation of body segments. Lewis investigated how genes could control the further development of individual body segments into specialized organs.

Where was Christiane nusslein Volhard born?

Magdeburg, Germany
Christiane Nüsslein-Volhard/Place of birth

When was Christiane Nüsslein Volhard born?

October 20, 1942 (age 78 years)
Christiane Nüsslein-Volhard/Date of birth

I was born during the war, on October 20, 1942, as the second of five children. My father, Rolf Volhard, was an architect.

What is the Heidelberg screen?

In large-scale mutagenesis screens performed in 1979-1980 at the EMBL in Heidelberg, we isolated mutations affecting the pattern or structure of the larval cuticle in Drosophila. Although the screens were initially driven entirely by curiosity, the mutants now serve as models for many human diseases.

How do balancer chromosomes work?

Balancer chromosomes keep homozygous lethal or sterile mutations from being lost from a population and they prevent multiple alleles on the same chromosome from being separated by meiotic recombination. All balancers have two essential features – recessive deleterious mutations and inversion breakpoints.

When was Christiane nusslein Volhard born?

Who was Linda Buck?

Linda B. Buck , (born January 29, 1947, Seattle, Washington, U.S.), American scientist and corecipient, with Richard Axel, of the Nobel Prize for Physiology or Medicine in 2004 for discoveries concerning the olfactory system.

How do you screen for mutations?

The screening process may include visual observations of the organisms’ appearances, behavioral tests, and physiological examinations. Once an abnormal phenotype is detected, the mutated gene can be identified by linkage mapping and the gene can be sequenced.