Questions and answers

What is a severely dysplastic nevus?

What is a severely dysplastic nevus?

A severely dysplastic nevus is indistinguishable from early melanoma. Very often these lesions show considerable irregularity of edge and irregularly irregular colour. The differentiation between a moderate and severely dysplastic nevus is one of degree. Mildly dysplastic nevi can be observed.

Is severe dysplastic nevus cancer?

Is it cancer? No. A dysplastic nevus is more likely than a common mole to become cancer, but most do not become cancer.

What percentage of dysplastic nevus becomes melanoma?

Congenital melanocytic nevi: Moles present at birth are called congenital melanocytic nevi. The lifetime risk of melanoma developing in congenital melanocytic nevi is estimated to be between 0 and 5%, depending on the size of the nevus.

Is dysplastic nevus benign or malignant?

Atypical moles, also known as dysplastic nevi, are unusual-looking moles that have irregular features under the microscope. Though benign, they are worth more of your attention because individuals with atypical moles are at increased risk for melanoma, a dangerous skin cancer.

Should dysplastic nevus be removed?

Dysplastic nevi can be classified as mild, moderate or severe. Mild is closer to benign, while moderate to severe is closer to melanoma. When diagnosed, most dermatologists will recommend that severe dysplastic nevi be removed as a precaution.

How serious is dysplastic nevus?

A dysplastic nevus may develop into melanoma (a type of skin cancer), and the more dysplastic nevi a person has, the higher the risk of melanoma.

Can a dysplastic nevus grow back?

Melanocytic nevi, including dysplastic or atypical nevi (DN), can recur or persist following shave removal procedures, and recurrence may resemble melanoma, both clinically and histologically (pseudomelanoma).

How often does dysplastic nevus turn into melanoma?

The authors estimated that the annual transformation rate of any single nevus into melanoma ranged from ≤1 in 200,000 for both men and women younger than 40 years to about 1 in 33,000 for men older than 60 years.

When should dysplastic nevus be removed?

Most dermatologists usually recommend that all patients with these severely dysplastic moles have them removed with a margin (0.5 cm-about a quarter inch) of clinically normal skin. Also many dermatologists recommend removing “moderate dysplasia” moles, if the biopsy didn’t get all of it.

How do you get rid of dysplastic nevi?

Surgical excision of the lesion with a 2- to 3-mm margin of normal skin followed by closure of the skin is the standard method for removal of a biopsy-diagnosed dysplastic nevus.

Can a nevus turn into melanoma?

Yes — but most dysplastic nevi do not turn into melanoma. Most types of atypical moles remain stable over time. Patients with five or more dysplastic nevi are 10 times more likely to develop melanoma than individuals with no atypical moles.

What causes dysplastic nevus?

What causes dysplastic nevi? Genetics and sun exposure combine to play a role in the development of dysplastic nevi. Sometimes they can develop on parts of the skin that received little or no sun exposure.

What should be the management of a dysplastic nevi?

Management of a biopsy-proven dysplastic (atypical) nevus with a positive histologic margin remains ill defined. Particularly after a biopsy finding of mildly or moderately dysplastic nevus with positive histologic margin, there is significant variation and lack of consensus in subsequent management.

Can a dysplastic nevi be associated with melanoma?

Dysplastic nevi are often graded as showing mild, moderate or severe atypia. They may be associated with an increased risk of melanoma particularly in a familial setting but also one not uncommonly sees a dysplastic nevus adjacent to a melanoma suggesting progression.

When did I get my dysplastic nevi biopsy?

A retrospective review of the University of Alabama Birmingham’s Department of Dermatology pathology database was performed. The review consisted of identifying biopsy reports between 2015 and 2017 that used the words “dysplastic” and “nevus.”

Why are there no margins on Nevi biopsy?

· Firstly with any given biopsy (even if the margins appeared clear) there was always concern that unless one literally serial sectioned the specimen, one could not be absolutely certain that a margin might be involved somewhere in the specimen.