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What is conventional osteosarcoma?

What is conventional osteosarcoma?

Conventional osteosarcoma is a high grade malignant primary central sarcoma of bonecharacterized by the presence of osteoid extracellular matrix.

Is osteosarcoma a fast growing cancer?

The types of osteosarcoma include: High-grade. This is fast-growing cancer. Most osteosarcoma in children is high-grade.

Is osteosarcoma highly malignant?

Osteosarcoma is a primary malignant tumour of the skeleton characterised by the direct formation of immature bone or osteoid tissue by the tumour cells. The classic osteosarcoma is a rare (0.2% of all malignant tumours) highly malignant tumour, with an estimated incidence of 3 cases/million population/year.

Will osteosarcoma leads to death?

Osteosarcoma, the most common malignant bone tumor, [1, 2] is a deadly form of musculoskeletal cancer that most commonly causes patients to die of pulmonary metastatic disease (see the image below).

Where is osteosarcoma most common?

Osteosarcoma most commonly happens in the long bones around the knee. Other sites for osteosarcoma include the upper leg, or thighbone, the lower leg, upper arm bone, or any bone in the body, including those in the pelvis, shoulder, and skull. Osteosarcoma may grow into nearby tissues, such as tendons or muscles.

What happens if osteosarcoma is left untreated?

If left untreated, primary bone cancer can spread to other parts of the body. Primary bone cancer is also known as bone sarcoma. Secondary (metastatic) bone cancer means that the cancer started in another part of the body, such as the breast or lung, and has spread to the bones.

Where does osteosarcoma usually start?

In children, teens, and young adults, osteosarcoma usually starts in areas where the bone is growing quickly, such as near the ends of the leg or arm bones: Most tumors develop in the bones around the knee, either in the lower part of the thigh bone (distal femur) or the upper part of the shinbone (proximal tibia).

Who is most at risk for osteosarcoma?

Age. The risk of osteosarcoma is highest for those between the ages of 10 and 30, especially during the teenage growth spurt. This suggests there may be a link between rapid bone growth and risk of tumor formation. The risk goes down in middle age, but rises again in older adults (usually over the age of 60).

Who is most likely to get osteosarcoma?