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What is meant by consensus sequence?

What is meant by consensus sequence?

A consensus sequence is a sequence of DNA, RNA, or protein that represents aligned, related sequences. In proteins, consensus sequences may represent entire protein molecules or short fragments of them that correspond to conserved regions of importance for structure and function.

How do you read a consensus sequence?

A consensus sequence is determined by aligning many nucleotide (or protein) sequences that share a common function, then determining the most commonly expressed nucleotide (or amino acid) at each position. Often conserved sequences reflect a common function or binding domain.

Why are they called consensus sequences?

What is a consensus sequence? Nucleotide sequences which share a common function, such as binding to the same protein, are often compared to see if they contain common nucleotides at fixed positions. The result usually is that they do — and the resulting sequence is often called a consensus sequence.

How do you create a consensus sequence in geneious?

You can also generate consensus sequences for single or multiple contig documents by selecting the documents and going to Tools → Generate Consensus Sequence.

What is a consensus DNA binding site?

Thus a consensus sequence is a model for a putative DNA binding site: it is obtained by aligning all known examples of a certain recognition site and defined as the idealized sequence that represents the predominant base at each position.

What is the difference between consensus and conserved sequence?

The key difference between conserved and consensus sequence is that conserved sequence refers to similar sequences of nucleic acids or amino acids that occur in different or same species over generations while consensus sequence is a commonly encountered nucleotides sequence or amino acid sequence found in a highly …

How do you generate consensus DNA sequence contig from forward and reverse sequence?

Popular Answers (1)

  1. Open the forward sequence (ABI format) with biodedit.
  2. select reverse seq, go to aligment, nucleic acid and reverse compliment.
  3. select both seq, go to pairwise alignment..
  4. From the new window generated, select both seq, go accessory application and create consensus sequence.