What is the most common cause of Hypotelorism?

It is often a result of fetal alcohol syndrome (FAS), caused by large alcohol intake in the first month of pregnancy. It can be associated with trisomy 13, which is also known as Patau syndrome, as well as hereditary neuralgic amyotrophy. It can also be associated with fragile X syndrome and Prader–Willi syndrome.

What is Hartsfield syndrome?

Hartsfield syndrome is a rare condition characterized by holoprosencephaly, which is an abnormality of brain development, and a malformation of the hands and feet called ectrodactyly. During early development before birth, the brain normally divides into two halves, the right and left hemispheres .

Is cystic hygroma a genetic disorder?

A cystic hygroma may be caused by genetic or environmental factors that cause abnormal development of the lymphatic vascular system during embryonic growth. It may occur on its own or as part of a genetic syndrome with other features, such as Turner syndrome, Down syndrome or Noonan syndrome.

What’s it called when your eyes are far apart?

Orbital hypertelorism is a condition in which the position of the bones around the eyes is further to the side than normal. This causes the eyes to be too far apart, grossly deforming the appearance. This can be corrected with a procedure called an orbital osteotomy.

Can holoprosencephaly be passed down?

Holoprosencephaly (HPE) can be inherited , but it is not always inherited. Inherited causes of holoprosencephaly may include: certain types of chromosome abnormalities. single gene mutations that cause syndromic disorders.

Is Ectrodactyly genetic?

Genetics. A large number of human gene defects can cause ectrodactyly. The most common mode of inheritance is autosomal dominant with reduced penetrance, while autosomal recessive and X-linked forms occur more rarely. Ectrodactyly can also be caused by a duplication on 10q24.

What chromosome is affected by Hartsfield syndrome?

Phenotype-Gene Relationships