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Which drug should not be given with zidovudine?

Which drug should not be given with zidovudine?

These drugs include methadone, rifampin, and some drugs used to treat seizures (such as phenytoin, valproic acid). This is not a complete list. This medication must not be taken with other medications that contain zidovudine.

What are the side effects of Combivir?

Headache, tiredness, loss of appetite, nausea, vomiting, diarrhea, trouble sleeping, dizziness, or stuffy nose may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Does Combivir cause anemia?

The AZT in Combivir can injure the bone marrow—the soft tissue inside bones where blood cells are made. As a result, Combivir can cause anemia (lowered red blood cell levels) and neutropenia (lowered neutrophil or white blood cell counts).

What is adverse effect of AZT?

AZT is a type of anti-HIV drug called a nucleoside analogue (“nuke”). The most common side effects of AZT can include headache, nausea, and loss of appetite. More rarely, it can cause anemia and low white blood cell counts. It is usually taken at a dose of 300 mg twice daily, with or without food.

Is AZT used to treat Epstein Barr virus?

In recent work, we have demonstrated that the thymidine nucleoside analog azidothymidine (AZT), alone and in combination with other antiviral agents, has in vitro and in vivo activity against lymphomas associated with Epstein-Barr virus (EBV) and human herpes virus type 8 (HHV-8).

Who can take Zidovudine?

Zidovudine is used along with other medications to treat human immunodeficiency virus (HIV) infection. Zidovudine is given to HIV-positive pregnant women to reduce the chance of passing the infection to the baby. Zidovudine is in a class of medications called nucleoside reverse transcriptase inhibitors (NRTIs).

How much does Combivir cost?

The cost for Combivir oral tablet (150 mg-300 mg) is around $951 for a supply of 60 tablets, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans. A generic version of Combivir is available, see lamivudine/zidovudine prices.

What is the generic name for Combivir?

Lamivudine (EPIVIR) and zidovudine (RETROVIR, azidothymidine, AZT, or ZDV) are synthetic nucleoside analogues with activity against HIV-1. COMBIVIR tablets are for oral administration.

Can lamivudine cause anemia?

Lamivudine-induced pure red cell aplasia may be a cause of anemia unresponsive to conventional treatment in AIDS. Since lamivudine use in Mexico has been relatively short, we expect more cases to appear in the future.

What is the adverse effect of zidovudine?

Zidovudine may cause blood and bone marrow problems. Symptoms of bone marrow problems include fever, chills, sore throat pale skin, or unusual tiredness or weakness. These problems may require blood transfusions or temporarily stopping treatment with zidovudine.

What is AZT short for?

The drug is usually referred to by its generic name, zidovudine, which is abbreviated to ZDV. The abbreviation AZT is sometimes used, which stands for azidothymidine. Its chemical name is 3′-azido-3′-deoxythymidine. Zidovudine is manufactured under the trade name Retrovir by GlaxoSmithKline.