How do you administer colistin IV?

I.V. colistin was given by infusion. Compatible infusion solutions are 0.9% sodium chloride injection, 5% fructose injection, 5% dextrose injection, and lactated Ringer’s injection. The powder in each vial is first dissolved in 3 mL of sterile water for injection (1 MU per 3 mL).

How do you mix colistin?

Inject 2mL of sterile water into the colistin vial, while gently rotating and swirling the bottle (to prevent foaming) until all the white powder has dissolved. DO NOT shake vigorously. 6. Withdraw 1mL (75mg) of the colistin and place it into the nebulizer.

How do you reconstitute colistimethate?

Reconstitute colistimethate sterile powder by adding 2 mL of sterile water for injection to a vial labeled as containing 150 mg of colistin; swirl gently to avoid frothing. Resultant solution contains 75 mg of colistin per mL. Add one-half of the total daily dose (as reconstituted solution) to a compatible IV solution.

How do you make Colistimethate sodium?

Reconstitute the colistimethate for injection with 2 mL of Sterile Water for Injection, producing a 75-mg/mL concentration of the drug. Gently swirl the solution to mix and to avoid frothing. Remove 0.24 mL of the solution; add sufficient Sterile Water for Injection to 15 mL and mix well.

How do you dilute IV colistin?

Colistin dosing instructions: Reconstitute each vial with 5 ml 0.9% sodium chloride, further dilute to 100 ml for loading dosage and 50 ml for maintenance dosage. Infusion loading dose over 60 minutes. Infuse maintenance dose over 15-30 minutes.

How do you use colistin injection?

Quick tips

1. Colistin Injection is an antibiotic that is usually only given in the hospital for serious infections.
2. It is given by injection or drip (infusion) into a vein usually over 30-60 minutes.
3. Finish the prescribed course, even if you start to feel better.
4. Diarrhea may occur as a side effect.

How much does colistin cost?

The cost for colistimethate injectable powder for injection (150 mg (colistin base)) is around $24 for a supply of 1 powder for injection, depending on the pharmacy you visit….Injectable Powder For Injection.

Does dexamethasone IV need to be diluted?

Oral dexamethasone doses only require dilution when doses smaller than or equal to 0.1mg are administered, to ensure accuracy of dose. Dilute 0.5mL of dexamethasone oral solution (1mg/mL) with 4.5mL of water for irrigation (to a total volume of 5mL).

Can colistin be given at home?

This medicine is for injection into a muscle or infusion into a vein. It is usually given by a health care professional in a hospital or clinic setting. If you get this medicine at home, you will be taught how to prepare and give this medicine. Use exactly as directed.

How much does colistin injection cost?

Questions & Answers on Colistimethate Sodium Injection

When do you use colistin?

Colistin is a polymyxin antibiotic administered as the prodrug colistimethate. Due to poor pharmacokinetics, administration of colistin intravenously is only recommended for urinary tract infections or as inhalation therapy for multi-drug resistant bacteria.

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