How do you give Herceptin IV?

How do you give Herceptin IV?

Administer Herceptin at an initial dose of 8 mg/kg as a 90-minute intravenous infusion followed by subsequent doses of 6 mg/kg as an intravenous infusion over 30–90 minutes every three weeks until disease progression [see Important Dosing Considerations].

How do you reconstitute Herceptin?

Reconstitute each 150 mg vial of Herceptin with 7.4 mL of Sterile Water for Injection (SWFI) (not supplied) to yield a single-dose solution containing 21 mg/mL trastuzumab that delivers 7.15 mL (150 mg trastuzumab).

How do you give Herceptin subcutaneous injection?

The recommended dose is 600 mg (in a solution of 5 mL). HERCEPTIN SC is given as a subcutaneous injection (under the skin) over 2 to 5 minutes every three weeks. The injection site should be alternated between the left and right thigh. New injections should be given at least 2.5 cm away from an old site.

Will hair grow back while on Herceptin?

Your hair may thin but you’re unlikely to lose all your hair. This usually starts after your first or second cycle of treatment. It is almost always temporary and your hair will grow back when you finish your treatment.

How does Herceptin make you feel?

The most common adverse reactions in patients receiving Herceptin in the adjuvant and metastatic breast cancer setting are fever, nausea, vomiting, infusion reactions, diarrhea, infections, increased cough, headache, fatigue, dyspnea, rash, neutropenia, anemia, and myalgia.

How long does Herceptin stay in system?

It would take 9.35 days for most of the Herceptin to be removed from your body. For a large 500mg dose of Herceptin given once weekly, the average half-life 12 days, it would take 66 days for most of the Herceptin to be removed from your body.

Do you lose your hair with Herceptin?

Answer: No, hair loss is not a common side effect of trastuzumab. If you are receiving trastuzumab in combination with chemotherapy, you may experience hair loss due to the chemotherapy.

Is Herceptin a form of chemotherapy?

Herceptin is an intravenous drug that is part of a chemotherapy regimen that is used to prevent recurrence of breast cancer, and for the treatment breast cancer that has spread beyond the breast (metastasized). It belongs to a class of drugs called monoclonal antibodies.

Does Herceptin lower your immune system?

Does trastuzumab (Herceptin) affect the immune system? Having trastuzumab (Herceptin) could mean you’re more at risk of getting coronavirus or becoming very ill if you get it. The risk is likely to be higher if you’re having it with chemotherapy.