Is Kaposiform Hemangioendothelioma malignant?

Kaposiform Hemangioendothelioma (KHE) is a rare vascular tumor of intermediate malignant potential which shows locally aggressive growth but only rarely metastasizes. It is mostly considered to be a tumor of pediatric population but its occurrence in the adults is not uncommon as once considered.

Is Khe a cancer?

Kaposiform hemangioendothelioma (KHE) may look like a birthmark, but is actually a rare benign tumor caused by the abnormal growth of blood vessels. It can appear anywhere on the body, often on the head and neck but also on the stomach, back, arms and legs — even inside the chest, abdomen or bones.

What is Kaposiform Hemangioendothelioma?

Kaposiform hemangioendothelioma, or KHE, is a type of tumor that grows in the blood vessels. Blood vessels help move blood around the body. This tumor usually grows just underneath the skin, but it can also grow deeper inside the chest or abdomen.

What is Hemangioendothelioma?

What is epithelioid hemangioendothelioma? Epithelioid hemangioendothelioma, or EHE, is a rare cancer that grows from the cells that make up the blood vessels. This cancer can occur anywhere in the body with the most common sites being the liver, lungs, and bone.

What is kasabach Merritt syndrome?

Kasabach-Merritt phenomenon (KMP) is a rare, potentially life-threatening condition. It occurs when certain fast-growing vascular tumors [kaposiform hemangioendothelioma (KHE) or tufted angioma (TA)] trap and destroy platelets, interfering with blood clotting and raising the risk of serious bleeding.

What is KLA disease?

Kaposiform lymphangiomatosis (KLA) is a rare type of tumor and vascular malformation that results from the abnormal development of the lymphatic system . The lymphatic system is part of the immune system made up of vessels that help to protect the body from infection and foreign substances.

Who is Khe hy?

Khe Hy left his position at BlackRock to become a writer and speaker focused on life’s tougher questions. CNN called him “Oprah for Millennials,” and Bloomberg dubbed him a “Wall Street guru” for spirituality.

What is an angiosarcoma?

Angiosarcoma is a rare cancer that develops in the inner lining of blood vessels and lymph vessels. This cancer can occur anywhere in the body but most often is in the skin, breast, liver and spleen.

What causes Hemangioendothelioma?

Hemangioendotheliomas are caused by abnormal growth of blood vessel cells , although the exact underlying cause for the abnormal growth is unknown. They can also develop in an organ , such as the liver or lung. They usually grow slowly and can sometimes spread to other tissues in the body (metastasize).

How long can you live with EHE?

Although localized epithelioid hemangioendothelioma can be surgically resected, there is no effective therapy for systemic disease, and mortality from the cancer ranges between 13% and 18% when confined to soft tissue, but life expectancy in metastatic cases is unpredictable and ranges from a couple of months to 15 to …

What causes Kasabach-Merritt syndrome?

Kasabach-Merritt syndrome is characterised by the combination of rapidly growing vascular tumour, thrombocytopenia, microangiopathic haemolytic anaemia and consumptive coagulopathy. The blood clotting disorder results from platelets and other clotting factors of the blood being used up within the tumor.

How is Kasabach-Merritt syndrome treated?

Management of Kasabach-Merritt syndrome (KMS) involves hastening vascular lesion regression, interfering with platelet trapping within the lesion, and supporting the patient with transfusions. Patients with KMS are admitted to the hospital with profound thrombocytopenia and evidence of coagulopathy.

Is the kaposiform hemangioendothelioma a benign tumor?

Kaposiform hemangioendothelioma (KHE) is a rare and aggressive vascular tumor that is benign (noncancerous and does not spread to other locations in the body).

What is the prognosis for hemangioendothelioma in humans?

The prognosis in each case depends on the type of hemangioendothelioma present, the risk of recurrence and whether the condition has metastasized (spread) to nearby tissues or other parts of the body.

Where are the blood vessels located in kaposiform hemangioendothelioma ( KHE )?

Kaposiform Hemangioendothelioma (KHE) is an infrequent and aggressive childhood tumor, involving the blood vessels. These tumors may be located on the skin surface, or deep inside the body tissues

What is the difference between kaposiform lymphangiomatosis and Khe?

Kaposiform lymphangiomatosis (KLA) and kaposiform hemangioendothelioma (KHE) are rare and aggressive vascular disorders. The aim of this study was to examine the clinical features and prognosis of KLA and KHE involving the thorax.