Is Zenatane the same as Accutane?

Zenatane, a therapeutic equivalent to Accutane, is approved for marketing only under a special restricted distribution program (iPLEDGE) approved by the Food and Drug Administration (FDA), as it can cause severe birth defects.

What is Zenatane used for?

This medication is used to treat severe cystic acne (also known as nodular acne) that has not responded to other treatment (e.g., benzoyl peroxide or clindamycin applied to the skin or tetracycline or minocycline taken by mouth). It belongs to a class of drugs known as retinoids.

Is Zenatane discontinued?

If this sounds familiar, it might be time to ask your doctor about isotretinoin. Commonly known by its original brand name Accutane, isotretinoin is a generic name that’s now marketed under various labels, including Absorica, Claravis, Amnesteem, and Zenatane. The brand name Accutane was discontinued in 2009.

Can you overdose on Zenatane?

Zenatane can hurt the tube that connects your mouth to your stomach (esophagus) if it is not swallowed whole. If you miss a dose, just skip that dose. Do not take two doses at the same time. If you take too much Zenatane or overdose, call your doctor or poison control center right away.

Does Zenatane cause depression?

Zenatane may cause depression, psychosis and, rarely, suicidal ideation, suicide attempts, suicide, and aggressive and/or violent behaviors.

Can you take Zenatane without food?

Swallow it whole. Follow all directions about taking Zenatane with or without food. Use Zenatane for the full prescribed length of time. Your acne may seem to get worse at first, but should then begin to improve.

Is Zenatane an antibiotic?

Zenatane is a form of vitamin A that is used to treat severe nodular acne that has not responded to other treatments, including antibiotics. Zenatane is available only from a certified pharmacy under a special program called iPLEDGE.

Has anyone died from Accutane?

Twelve deaths were recorded in 2019, 10 by suicide, by people who had been prescribed Roaccutane, according to data from the Medicines and Healthcare Products Regulatory Agency (MHRA). The figure is up from five fatalities the year before and is the highest since records began in 1983.

Is Accutane still on the market 2020?

Generic versions of the acne drug, called isotretinoin, are still available from several manufacturers. But Roche, which has sold the drug to 13 million patients since 1982, will not be one of them. The decision was made for “business reasons,” Roche announced in a news release.

Has anyone ever died from Accutane?

What happens if I accidentally take 2 Accutane?

Do not take two doses at the same time. If you take too much Accutane or overdose, call your doctor or poison control center right away. Your acne may get worse when you first start taking Accutane. This should last only a short while.

Can Accutane cause anger?

If you decide to go forward with isotretinoin treatment, there’s no reason to be anxious. While you (or your child) is taking Accutane, watch for any symptoms of depression, like: Changes in mood and behavior. Feeling unusually sad, angry, irritable, or aggressive.

Are there any side effects to taking Zenatane?

Common side effects of Zenatane include: cheilitis, epistaxis, hypertriglyceridemia, pruritus, xerosis cutis, decreased hdl cholesterol, increased liver enzymes, increased serum triglycerides, musculoskeletal signs and symptoms, dry nose, xeroderma, and xerostomia.

What are the half lives of Zenatane for children?

In pediatric patients (12 to 15 years), the mean ± SD elimination half-lives (t 1/2) of isotretinoin and 4-oxo-isotretinoin were 15.7 ± 5.1 hours and 23.1 ± 5.7 hours, respectively. The accumulation ratios of isotretinoin ranged from 0.46 to 3.65 for pediatric patients. Zenatane is indicated for the treatment of severe recalcitrant nodular acne.

Is it safe to take Zenatane with parabens?

Zenatane is contraindicated in patients who are hypersensitive to this medication or to any of its components (see PRECAUTIONS: Hypersensitivity). Zenatane should not be given to patients who are sensitive to parabens, which are used as preservatives in the gelatin capsule.

How many Zenatane capsules are in a pack?

Zenatane (isotretinoin capsules USP) 40 mg are opaque green elliptical soft gelatin capsules imprinted with black ink, “R137” on one side and are supplied in boxes of 30 containing 3 prescription packs of 10 capsules and 100 containing 10 prescription packs of 10 capsules, as unit dose blisters.