What is MTTP gene?

The MTTP gene provides instructions for making a protein called microsomal triglyceride transfer protein.

What does microsomal triglyceride transfer protein do?

Microsomal triglyceride transfer protein (MTP) plays an essential role in lipid metabolism, especially in the biogenesis of very low-density lipoproteins and chylomicrons via the transfer of neutral lipids and the assembly of apoB-containing lipoproteins.

What does MTTP stand for?

MTTP

What is MTP enzyme?

The microsomal triglyceride transfer protein (MTP) is a lipid transfer protein involved in the assembly and secretion of apolipoprotein-B-containing lipoproteins (Hooper et al., 2015); it transfers neutral lipids (triglycerides and cholesteryl esters) from the endoplasmic reticulum membrane to the nascent apoB (Hooper …

Are proteins part of triglycerides?

Fats, a subgroup of lipids, are also known as triglycerides, meaning their molecules are made from one molecule of glycerol and three fatty acids. Proteins are polymers of hundreds or even thousands of amino acids. Each protein has a different structure and performs a different function in the body.

What do apolipoproteins do?

Apolipoproteins. Apolipoproteins are amphipathic molecules capable of interacting with both the lipids of the lipoprotein core and the aqueous environment of the plasma. They function as biochemical keys, allowing lipoprotein particles access to specific sites for the delivery, acceptance, or modification of lipids.

What does a triglyceride consist of?

Triglycerides are the most common form of fat in the bloodstream. They consist of three fatty acid chains linked by a molecule called glycerol. When you eat food, enzymes in your gut break down fats into their component fatty acids, which are then reassembled to create triglyceride particles.

What does MPPT mean in solar?

Maximum Power Point Tracking
This section covers the theory and operation of “Maximum Power Point Tracking” as used in solar electric charge controllers. An MPPT, or maximum power point tracker is an electronic DC to DC converter that optimizes the match between the solar array (PV panels), and the battery bank or utility grid.

What are the 4 types of lipoproteins?

There are four major classes of circulating lipoproteins, each with its own characteristic protein and lipid composition. They are chylomicrons, very low-density lipoproteins (VLDL), low-density lipoproteins (LDL), and high-density lipoproteins (HDL).

What kind of protein does the MTTP gene make?

The MTTP gene provides instructions for making a protein called microsomal triglyceride transfer protein. This protein helps produce beta-lipoproteins, which are molecules that are made up of proteins (including one called apolipoprotein B), cholesterol, and particular types of fats called phospholipids and triglycerides.

Which is anti sense strand of the MTTP gene?

The anti-sense strand of the mouse Mttp gene contains one noncoding RNA. microsomal triglyceride transfer protein, a protein involved in the transfer of lipids onto CD1d, regulates liver natural killer T cell homeostasis in a manner dependent on hepatocyte CD1d.

Where is the MTP gene located in mouse?

By PCR analysis of rodent/human somatic cell hybrids followed by fluorescence in situ hybridization, Narcisi et al. (1995) mapped the MTP gene to 4q22-q24. By Southern blots of interspecific backcross panels, Nakamuta et al. (1996) mapped the mouse Mtp gene to distal chromosome 3.

What is the role of MTP in lipoprotein assembly?

Gene ID: 4547, updated on 8-Jul-2018. MTP encodes the large subunit of the heterodimeric microsomal triglyceride transfer protein. Protein disulfide isomerase (PDI) completes the heterodimeric microsomal triglyceride transfer protein, which has been shown to play a central role in lipoprotein assembly.