What is naphthylamine used in?

2-Naphthylamine now is used only in laboratory research. It formerly was used as an intermediate in the manufacture of dyes, as an antiox- idant in the rubber industry, and to produce 2-chloronaphthylamine (IARC 1974, HSDB 2009).

Is 2-naphthylamine soluble in water?

2-naphthylamine is a naphthylamine carrying the amino group at position 2. It has a role as a carcinogenic agent. Beta-naphthylamine appears as a white to reddish colored solid in the form of flakes. Slightly soluble in hot water and denser than water.

Is naphthalene an amine?

1-Naphthylamine is an aromatic amine derived from naphthalene. It can cause bladder cancer (transitional cell carcinoma). It crystallizes in colorless needles which melt at 50 °C. It possesses a disagreeable odor, sublimes readily, and turns brown on exposure to air.

Is 2 naphthylamine a carcinogen?

The National Institute for Occupational Safety and Health (NIOSH, 2005) lists 2-naphthylamine as one of 13 OSHA-regulated carcinogens. Exposures of workers are to be controlled through the required use of engineering controls, work practices, and personal protective equipment, including respirators.

What is benzidine used for?

Benzidine-based dyes are used in the production of textiles, paints, printing inks, paper, and pharmaceuticals. They are also used as reagents and biological stains in laboratories, and have more recent uses in laser, liquid crystal displays, ink-jet printers, and electro-optical devices.

Is diphenylamine soluble in water?

The compound is a colorless solid, but commercial samples are often yellow due to oxidized impurities. Diphenylamine dissolves well in many common organic solvents, and is moderately soluble in water. It is used mainly for its antioxidant properties.

What is the chemical name of naphthalene?

Naphthalene

Is benzidine A?

What is benzidine? Benzidine is a manufactured chemical that does not occur in nature. In the past, large amounts of benzidine were used to produce dyes for cloth, paper, and leather. It was also used in clinical laboratories for detecting blood, as a rubber-compounding agent, and in the manufacture of plastic films.

How does 2-naphthylamine play a role in disease?

Role in disease. 2-Naphthylamine is found in cigarette smoke and suspected to contribute to the development of bladder cancer. It is activated in the liver but quickly deactivated by conjugation to glucuronic acid. In the bladder, glucuronidase re-activates it by deconjugation, which leads to the development of bladder cancer.

When did Dupont stop using 2-naphthylamine dye?

2-Naphthylamine was previously used as a dye precursor and rubber antioxidant in the 1930s, 40s and 50s. Dupont stopped using it in the 1970s.

Where is 2-naphthylamine found in cigarette smoke?

2-Naphthylamine is found in cigarette smoke and suspected to contribute to the development of bladder cancer. It is activated in the liver but quickly deactivated by conjugation to glucuronic acid.

Which is the amino group at position 2 in naphthylamine?

2-naphthylamine is a naphthylamine carrying the amino group at position 2. It has a role as a carcinogenic agent. Beta-naphthylamine appears as a white to reddish colored solid in the form of flakes.