What is the Konno procedure?

The Ross-Konno procedure is an open-heart surgery done under general anesthesia and cardiopulmonary bypass. It involves removing the damaged aortic valve, removing the pulmonary valve, and putting the pulmonary valve in place of the damaged aortic valve.

Is the Ross procedure open heart surgery?

During the Ross open heart surgical procedure, the diseased aortic valve is removed and replaced with the patient’s biologic pulmonary valve. A second pulmonary valve, typically a homograft (human tissue) valve or occasionally an animal tissue valve, is then attached to function as a new pulmonary valve.

What is Konno?

The Ross–Konno operation is a complex procedure for severe or multilevel (sub)aortic stenosis. It consists of using the patients’ pulmonary valve as a neoaortic autograft (Ross procedure), combined with the opening of a narrowed left ventricular outflow tract (LVOT) by incising the outflow septum.

What is pulmonary homograft?

Pulmonary homografts consist of the muscle shelf, pulmonary valve, and proximal pulmonary artery harvested from a human cadaver. They are prepared fresh with antibiotic solution, or cryopreserved, and have proven useful in the reconstruction of both the right and left ventricular outflow tracts.

How long does Ross procedure take?

The Ross Procedure typically takes 4 – 6 hours.

What is shone’s disease?

Shone’s syndrome (also known as Shone’s complex) is a rare combination of four left-sided congenital cardiac anomalies including parachute mitral valve, supravalvar mitral ring, coarctation (narrowing) of the aor- ta, and subaortic obstruction.

What are the disadvantages of Ross procedure?

Disadvantages include: 1) the procedure is more complex than standard aortic valve replacement because two cardiac valves are involved; 2) the operation is technically more demanding.

What is Lvot and Rvot?

The right ventricular outflow tract (RVOT) is an infundibular extension of the ventricular cavity that connects to the pulmonary artery. The left ventricular outflow tract (LVOT), which connects to the aorta, is nearly indistinguishable from the rest of the ventricle.

How long does a homograft valve last?

Homograft valves are expected to last about 15 to 20 years. Like bioprosthetic valves, homografts are not as durable in younger patients. The Ross procedure is usually performed on patients younger than ages 40 to 50 who want to avoid taking long-term anticoagulant medications after surgery.

What is homograft rejection?

Homograft valves are usually transplanted without matching donor and recipient for blood group or human leukocyte antigens (HLA). Theoretically, the lack of blood vessels in cardiac valves should protect them from rejection.

How successful is the Ross procedure?

Ross procedure patients experienced superior unadjusted long-term survival at 20 years (Ross, 95%; mechanical, 68%; p < 0.001). Multivariable analysis showed the Ross procedure to be associated with a reduced risk of late mortality (hazard ratio: 0.34; 95% confidence internal: 0.17 to 0.67; p < 0.001).