Which organs Cannot regenerate?

The liver is the only organ in the human body that can regenerate. Although some patients who have a diseased portion of their liver removed are unable to regrow the tissue and end up needing a transplant. Researchers from Michigan State University believe blood clotting factor fibrinogen may be responsible.

Can the heart repair itself?

But the heart does have some ability to make new muscle and possibly repair itself. The rate of regeneration is so slow, though, that it can’t fix the kind of damage caused by a heart attack. That’s why the rapid healing that follows a heart attack creates scar tissue in place of working muscle tissue.

Which is the biggest muscle in the human body?

gluteus maximus
The gluteus maximus is the largest muscle in the human body. It is large and powerful because it has the job of keeping the trunk of the body in an erect posture. It is the chief antigravity muscle that aids in walking up stairs.

What is the only body part that Cannot repair itself?

Teeth
Teeth are the ONLY body part that cannot repair themselves. Repairing means either regrowing what was lost or replacing it with scar tissue. Our teeth cannot do that. Our brain for example will not regrow damaged brain cells but can repair an area by laying down other scar-type tissue .

How are H9C2 cells used as an alternative for cardiomyocytes?

H9c2 myoblasts are a cell model used as an alternative for cardiomyocytes. H9c2 cells have the ability to differentiate towards a cardiac phenotype when the media serum is reduced in the presence of all-trans-retinoic acid (RA), creating multinucleated cells with low proliferative capacity.

Is the H9c2 cardiomyoblast cell line animal free?

In addition, some studies make use of the H9C2 rat cardiomyoblast cell line, which has the advantage of being an animal-free alternative; however, the extent to which H9C2 cells can accurately mimic the hypertrophic responses of primary cardiac myocytes has not yet been fully established.

Is the H9c2 cell line a risk factor for heart failure?

The H9C2 cell line and primary neonatal cardiomyocyte cells show similar hypertrophic responses in vitro Cardiac hypertrophy is a major risk factor for heart failure and associated patient morbidity and mortality.

Why are H9C2 cells more resistant to hypoxia?

We demonstrate that H9c2 cells are significantly more sensitive to hypoxia-reoxygenation injury in terms of loss of cell viability and mitochondrial respiration, whereas HL-1 cells were more resistant to hypoxia as evidenced by their relative stability.