What is a male pseudohermaphrodite?
What is a male pseudohermaphrodite?
Male pseudohermaphroditism is the condition of incomplete male differentiation of the external genitalia in an individual with a Y chromosome. The gonads of the male pseudohermaphrodite, when present, are either streak gonads or testes.
How common is male pseudohermaphroditism?
Male pseudohermaphroditism is rare and almost always results from autosomal recessive genetic defects (defects that must be inherited from both parents in order to be expressed). Several specific defects lead to feminization in genetic males.
What is the difference between pseudohermaphrodite and hermaphrodite?
By definition, true hermaphrodites have external genitalia and gonads of both genders, whereas pseudohermaphrodites have external phenotypes opposite the genotype but internal genitalia consistent with the genotype.
What are the causes of pseudohermaphroditism?
Congenital adrenal hyperplasia (CAH), mostly 21-hydroxylase deficiency, is the most common cause. Maternal androgen excess due to maternal ovarian tumor or drug intake also causes female pseudohermaphroditism. Combination of hormonal therapy and surgical correction is required for CAH.
How do I know if I am intersex?
If a person’s genitals look different from what doctors and nurses expect when they’re born, someone might be identified as intersex from birth. Other times, someone might not know they’re intersex until later in life, like when they go through puberty.
What do you call a human with both sexes?
hermaphroditism, the condition of having both male and female reproductive organs. Affected individuals have sex chromosomes showing male-female mosaicism (where one individual possesses both the male XY and female XX chromosome pairs).
How do I know if Im a hermaphrodite?
Signs and symptoms
- Ambiguous genitalia.
- Micropenis.
- Clitoromegaly.
- Labial fusion.
- Undescended testes.
- Hypospadias.
- Electrolyte abnormalities.
- Delayed, absent or abnormal pubertal changes.
What are the signs of being a hermaphrodite?
Signs and symptoms
- Ambiguous genitalia.
- Micropenis.
- Clitoromegaly.
- Labial fusion.
- Undescended testes.
- Hypospadias.
- Electrolyte abnormalities.
- Delayed, absent or abnormal pubertal changes.
Can a hermaphrodite have babies with itself?
Hermaphrodites can either reproduce by virtue of self-fertilization or they can mate with a male and use the male derived sperm to fertilize their eggs. While virtually the entire progeny that is produced by self-fertilization is hermaphroditic, half of the cross-progeny is male.
Is pseudohermaphroditism a disorder?
Female pseudohermaphroditism occurs when normal ovaries are present but the body is partially masculinized. Examples are individuals with congenital adrenal hyperplasia (CAH), also known as adrenogenital syndrome (Figure 5.9). This is an inherited disorder that can develop after, but usually occurs before, birth.
Can intersex give birth?
If an intersex person has a uterus, they may be able to carry a pregnancy. If they have ovaries or ovotestes, that tissue could be used for reproduction in some cases. Some intersex people do have ovaries, a uterus, and a vagina, and could get pregnant by contact with sperm.
Can intersex males get pregnant?
Can intersex people reproduce? If an intersex person has a penis and testes that make sperm, they may be able to cause a pregnancy. Some intersex people have a vulva, vagina, and internal testes. Those testes might contain tissue that could be used to reproduce, with technology’s help in the future.
Can a pseudohermaphrodite be assigned a female gender at birth?
Male pseudohermaphrodites with poor penile development who have testosterone biosynthetic defects or androgen resistance are usually assigned to the female gender. However, for those with 5α-reductase or 17β-hydroxysteroid reductase deficiency, it may not be appropriate to assign a gender at birth.
Are there two types of pseudohermaphroditism in the world?
There are two varieties of pseudohermaphroditism: female pseudohermaphroditism, known now as XX intersex, and male pseudohermaphroditism, or XY intersex. People with XX intersex have the chromosomes and ovaries of a female but external genitalia that appear male, such as an enlarged clitoris and fused labia that resemble a scrotum.
What causes male pseudohermaphroditism on the X chromosome?
The two primary causes of male pseudohermaphroditism are androgen insensitivity syndrome and 5-alpha reductase deficiency. This is called androgen insensitivity syndrome because male babies don’t respond to testosterone (androgens). This syndrome is inherited. It is caused by a problem with a gene on the X chromosome.
Are there any cases of pseudohermaphroditism in the Dominican Republic?
Another form of male pseudohermaphroditism has been described in the populations of some small villages in the Dominican Republic (see Box 5.2 and Figure 5.9 ). FIGURE 5.9. Examples of intersexuality in which external sexual characteristics differ from genetic and gonadal sex. The degree of feminization or masculinization varies among individuals.